LONDON — Sanofi and GlaxoSmithKline say they are beginning human trials of a potential vaccine for COVID-19 after positive results from preclinical testing.
The drugmakers said Thursday they plan to test the vaccine on 440 adults at 11 sites in the U.S., with the first results expected in early December. If these tests are successful, the companies plan to begin large-scale trials later that month.
Sanofi and GlaxoSmithKline say they plan to seek regulatory approval for the vaccine in early 2021 if data from the trials supports it.
The two companies in July announced plans to collaborate with the U.S. government to produce up to 100 million doses of the vaccine, with the government taking an option to purchase up to 500 million more doses in the future. The British government has agreed to buy up to 60 million doses.
HERE’S WHAT YOU NEED TO KNOW ABOUT THE VIRUS OUTBREAK
— CDC tells states: Be ready to distribute vaccines on Nov. 1
— Critics: Eviction ban may only delay wave of homelessness
— Former Italian premier Berlusconi tests positive for COVID
— Amnesty International says Mexico leads the world in coronavirus deaths among its health care workers. The group says Mexico has reported 1,320 confirmed deaths from COVIID-19 so far, surpassing the United States at 1,077, the United Kingdom at 649, and Brazil at 634.
— New studies confirm that multiple types of steroids improve survival for severely ill COVID-19 patients, cementing the cheap drugs as a standard of care.
— Scientists are reporting that the antibodies people make to fight the new coronavirus do not fade quickly. The new study is the most extensive work yet on the immune system’s response to the virus and is good news for efforts to develop vaccines.
HERE’S WHAT ELSE IS HAPPENING:
ANKARA, Turkey — Turkey is expanding restrictions imposed on social gatherings such as wedding and engagement parties and henna nights in more than a dozen provinces to the entire country.
An Interior Ministry circular sent to Turkey’s 81 provinces late Wednesday says such social gatherings will banned from Friday. Marriage registration ceremonies will be allowed but will be restricted to one hour only.
The decision came after the health minister said the country is experiencing the second peak of the first wave of the coronavirus outbreak and blamed gatherings at weddings and holidays.
The number of daily infections have tipped above 1,500 — levels previously seen in mid-June. More than 273,000 people have tested positive for the virus in Turkey since March.
PRAGUE — The Czech Republic has registered the biggest day-to-day increase in the new confirmed cases of COVID-19.
The Health Ministry says a record 650 people tested positive on Wednesday, up from 504 on Tuesday.
Health Minister Adam Vojtech says new restrictions are likely to be imposed.
Vojtech is currently quarantined after a senior official in his department tested positive for COVID-19.
The Czech Republic has had 25,773 confirmed infections with 425 deaths.
LOS ANGELES — The Los Angeles City Council has declared a fiscal emergency because of the coronavirus pandemic, paving the way to furlough about 15,000 employees.
Wednesday’s declaration comes as the city looks at a tax shortfall this year of up to $400 million.
Mayor Eric Garcetti is expected to approve the measure.
The furloughs, which would begin Oct. 11, would require civilian employees to take up to 18 days off from work. But a labor union official tells the Los Angeles Daily News that the furloughs violate labor contracts and will be vigorously fought.
BEIJING — Beijing’s main international airport on Thursday began again receiving international flights from a limited number of countries considered at low risk of coronavirus infection.
Passengers flying in from Cambodia, Greece, Denmark, Thailand, Pakistan, Austria, Canada and Sweden, must have first shown a negative nucleic acid test for coronavirus before boarding, city government spokesperson Xu Hejian told reporters.
Passenger arrivals will be limited to roughly 500 per day during an initial trial period and all will need to undergo additional testing for the virus on arrival, followed by two weeks of quarantine. The first flight under the new arrangement, Air China 746, arrived from Pnom Penh, Cambodia just before 7 a.m.
Beginning in March, all international flights to Beijing had been redirected to a dozen other cities where passengers were tested and processed before being allowed to travel on to the Chinese capital.
China has gone weeks without new cases of local infection and on Thursday recorded 11 cases brought from outside the country. China has recorded a total of 4,634 deaths from COVID-19 among 85,077 cases since the virus was first detected in the central Chinese city of Wuhan late last year, sparking the global pandemic.
LOS ANGELES — Dwayne “The Rock” Johnson says he and his family tested positive for the coronavirus.
Johnson announced their diagnosis in an 11-plus minute video on Instagram on Wednesday.
The actor says he was shocked after hearing their positive tests. He called the ordeal “one of the most challenging and difficult things we’ve had ever to endure.”
The actor said he along with wife, Lauren Hashian, and two young daughters contracted the virus, but have now recovered.
He says his daughters “bounced back” after having sore throats for a couple days. But for Johnson and his wife, he says they both had a “rough go.”
SAN DIEGO — San Diego State University has halted in-person classes for a month after dozens of students were infected with the coronavirus.
The school announced Wednesday that about 200 course offerings, some of them lab classes, will move to virtual learning. On-campus housing will remain open.
San Diego County health officials say there have been 64 confirmed or probable cases of COVID-19 among SDSU students since classes resumed last week. Some, but not all, of the infections were linked to other cases at the university. Some involve students who live off-campus.
California State university at Chico also halted classes this week.
SANTA FE, N.M. — A top state health official is warning that COVID-19 infections are far more prevalent in low-income areas of the New Mexico, potentially straining Medicaid health care.
Human Services Secretary David Scrase said Wednesday that an analysis of infection rates by census tract shows that highly impoverished areas have infection rates seven times higher than the most affluent zones.
Scrase and Children Youth and Families Secretary Brian Blalock gave a briefing on public health trends and the state’s coronavirus response.
State health officials are wary that festivities over the Labor Day holiday weekend could lead to renewed surges in COVID-19 infections.
URBANA, Ill. — The University of Illinois is ramping up enforcement of restrictions on student activity after more than 330 COVID-19 cases in two days on the school’s Urbana-Champaign campus, school officials said Wednesday.
In an email to students, Chancellor Robert Jones said he expects all undergraduates to “limit their in-person interactions to only the most essential activities” for the next two weeks starting Wednesday evening.
“These include things like taking twice weekly COVID-19 tests, attending class, purchasing groceries and food, going to work, engaging in individual outdoor activity, attending religious services and seeking medical attention,” Jones wrote.
The University of Illinois isn’t the only university in the state seeing a spike in COVID-19 cases. Illinois State University in Normal is reporting about 1,025 students have tested positive since the start of the fall semester two weeks ago, nearly 5% of the student body.
Since students returned to the Urbana-Champaign campus Aug. 16, more than 1,000 people on campus have tested positive. University officials say about 800 people are currently in quarantine.
ATLANTA — With more than 3,000 public university students and employees across Georgia testing positive for COVID-19 since Aug. 1, some schools are taking action to slow the spread of the respiratory illness.
Georgia Tech is encouraging students to convert to single rooms, moving out roommates over coming weeks to reduce exposure to the coronavirus. Both Georgia Tech and the University of Georgia announced they are renting more off-campus rooms to isolate or quarantine students who have been infected or exposed to the virus.
The University of Georgia reported 821 new infections for the week ended Saturday, a number that President Jere Morehead said Wednesday is “concerning.” He urged students to “continue to make every effort to prioritize their health and safety by taking the proper steps to avoid exposure to this virus.
Around 4% of all cases recorded in Georgia in the last month have been associated with university campuses, according to figures kept by The Associated Press. The number could be higher because some schools, including the state’s largest — Georgia State University — are not posting full reports publicly.
The rising campus infection numbers come as new cases in the rest of Georgia decline. The total number of cases rose to near 275,000 Wednesday, according to state data, but the average number of cases has fallen below 2,000 a day.
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